Not yet reviewed by Pith; the record is open.

Abrikosov vortices, where the superconducting gap is completely suppressed in the core, are dissipative, semi-classical entities that impact applications from high-current-density wires to superconducting quantum devices. In contrast, we present evidence that vortices trapped in granular superconducting films can behave as two-level systems, exhibiting microsecond-range quantum coherence and energy relaxation times that reach fractions of a millisecond. These findings support recent theoretical modeling of superconductors with granularity on the scale of the coherence length as tunnel junction networks, resulting in gapped vortices. Using the tools of circuit quantum electrodynamics, we perform coherent manipulation and quantum non-demolition readout of vortex states in granular aluminum microwave resonators, heralding new directions for quantum information processing, materials characterization, and sensing.